Overview of Selected Chemical Compounds and Intermediates

Overview of Selected Chemical Compounds and Intermediates

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1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is certainly an impurity associated with bortezomib, a proteasome inhibitor used in the treatment method of a number of myeloma. Its synthesis or research is critical for making certain the purity and safety of the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-7): A precursor within the synthesis of abiraterone acetate, a drug Utilized in the procedure of prostate most cancers by inhibiting androgen manufacturing.
Imatinib Intermediate (CAS NO. 152460-10-one): A crucial compound within the synthesis of imatinib, a drug that targets unique sorts of cancer, which include chronic myelogenous leukemia (CML).
Docetaxel Intermediate: A compound used in the synthesis of docetaxel, a chemotherapy medication that treats different cancers which include breast, lung, and prostate most cancers.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, 8): These are generally intermediates within the synthesis of gemcitabine, an anti-cancer drug. Their research is important for optimizing the production approach and making certain large purity.
Lapatinib Intermediate (CAS NO. 231278-84-5): Lapatinib is made use of to treat breast most cancers, and these intermediates are associated with its manufacturing.
Fulvestrant Intermediates: Fulvestrant is surely an estrogen receptor antagonist used in the therapy of breast most cancers. Many intermediates assist in the synthesis of the drug.
Paclitaxel Side Chain Acid (CAS NO. 949023-16-nine): This intermediate is Employed in the synthesis of paclitaxel, a chemotherapy drug successful in managing cancers for instance ovarian, breast, and lung most cancers.
three. Other Noteworthy Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-three): A chemotherapy drug Utilized in the cure of colorectal most cancers and smaller mobile lung cancer.
3-Amino-1-hydroxyadamantane (CAS 702-82-9): This compound is associated with Bortezomib Acid Impurity the synthesis of adamantane derivatives, that have several purposes, together with antiviral Qualities.
Vildagliptin Intermediates: Employed in the production of vildagliptin, an oral drug for type 2 diabetes that inhibits the enzyme DPP-four to control blood sugar degrees.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-one): This compound is involved with the synthesis of varied gluconic acid derivatives, which might be Utilized in foodstuff, pharmaceutical, and industrial apps.
Canagliflozin Intermediate 2: A precursor inside the synthesis of canagliflozin, a medication utilised to handle sort two diabetic issues by 6-Iodo-4-[3-chloro-4-(3-fluorobenzyloxy)anilino]quinazoline inhibiting sodium-glucose co-transporter two (SGLT2).